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Research conducted at the East Avenue Medical Center involving human participants is overseen by the Institutional Ethics Review Board (IERB). Its purpose is to facilitate clinical research and to ensure that the rights and welfare of human subjects are protected during their participation in the research study.

East Avenue Medical Center upholds the highest standards in the ethical conduct of research, including the protection of human participants, while enabling its fellows, residents, staff and affiliate students to conduct research in a timely and efficient manner. The primary mission of the Institutional Ethics Review Board (IERB) is to facilitate those objectives by reviewing, approving, modifying or disapproving research protocols submitted by researchers based on current practices and standards of research ethics.

The EAMC IERB process is based on Philippine laws and regulations, standards of professional conduct and practice with sensitivity to cultural differences and community values. It has the primary responsibility to protect the rights and welfare of the human participants involved in clinical investigations. It evaluates research according to the provisions of the Helsinki Declaration, International Conference of Harmonization Good Clinical Practice (ICH GCP), Guidelines on the Conduct of Biomedical Research, National Ethics Guidelines for Health Research and other international and national guidelines and policies.

The EAMC IERB strives to create a culture of respect for, and awareness of, the rights and welfare of human research participants, while advancing knowledge and facilitating the highest quality research.

The EAMC IERB regularly meets every 3rd Wednesday of the month. The members deliberate and review research proposals from pharmaceutical companies, of fellows, residents, consultants and other individuals who are interested in conducting their research at the East Avenue Medical Center.

The EAMC IERB is a Level III Research Ethics Committee with Philippine Health Research Ethics Board (PHREB) Accreditation No. L3-2016-026-01 effective 3 March 2016.